Ozone Therapy For Animals

Part I – Viral (Rickettsial and Chlamydial) Diseases (VRCDs)
Ozone is very effective in acute and chronic viral diseases as a virucidal agent in reversing positive antibody tests and in improving the general health of the animals. Ozone is the treatment of choice of Equine Infectious Enema (EIA, Swamp fever) and promptly reverses the clinical symptoms and a positive Coggins test. Ozone is equally effective against Equine Ehrlichiosis and Potomac Horse Fever, caused by the rickettsial agents Ehrlichia equi and E. risticii respectively, as well as against Equine Encephalomyelitis (EE) including Eastern (EEE), Western (WEE), Venezuelan (VEE) and other togaviral and flaviviral EE, Equine Viral Arteritis, African Horse Sickness (AHS), Equine Herpesvirus I (EHV-1) infection, Equine Viral Rhinopneumonitis and Myeloencephalopathy, Equine Influenza and other VRCDs of horses and other animals including cattle, (e.g. chlamydial abortion from Chlamydia psittaci, et al.), cats, dogs, sheep, goats, domestic birds and various zoo animals.

Part II – Respiratory Diseases of Horses
Ozone is effective against respiratory viral infections (RVIs) (see part I) such as RVIs caused by EHV-1 (rhinopneumonitis), equine arteritis virus, rhonovirus, influenza as well as adenovirus pneumonia with combined immunodeficiency in Arabian foals. Ozone is also effective against viral respiratory infections with secondary bacterial infection (see part III) that produces mucopurulent nasal discharge, exacerbates the cough, and may lead to lung abscessation, pneumonia or pleurisy. For ozone treatment of COPD (heaves), see part IV.

Ozone is the treatment of choice for Exercise-Induced Pulmonary Hemorrhage (EIPH, Epistaxis, “Bleeder”), especially in States and Countries that do not allow furosemide (LasixR). In most cases ozone reverses the bronchitis, neovascularization and fibrosis, and through a homeopathic mechanism, the other contributory factors of EIPH in “bleeders”.

Part III – Bacterial Diseases
Ozone is very effective for acute and chronic bacterial diseases, including those that do not respond well to antibiotics such as Glanders (Pseudomonas mallei); Septicemia in foals (e.g. from E. coli, Klebsiella spp., Actinobacillus spp.); Leptospirosis (Leptospira interrogans); Listeriosis (Listeria monocytogenes); ContagiousEquine Metritis (CEM from Taylorella equigenitalis); retained placenta with consecutive metritis, septicemia and laminitis; Tularemia (Francisella tularensis); Clostridial diseases e.g. Tetanus Enterotoxemia (Cl. perfringens infection); Malignant Edema (Cl. septicum); Botulism and Infectious Necrotic Hepatitis (Cl. novyi); Lyme Disease (Borrelia burgdorferi); Actinobaccilosis (e.g. A. equuli in horses); Anthrax; Melioidosis hematogenous septic polyarthritis with primary Brucellosis (Brucella melitensis, B. abortus, B. suis, B. canis, B. ovis, B. neotomae) and others, especially in valuable race horses and zoo animals.

Part IV – Fungal Diseases
Ozone is effective against systemic Actinomycosis and Candidiasis, Chromomycosis, North American Blastomycosis, Histoplasmosis, Aspergillosis and is a valuable adjunct in Chronic Obstructive ulmonary Disease (COPD, heaves) of horses. In the treatment of heaves, ozone relieves acute “asthmatic” attacks and the paroxysmal cough and effectively preverses the allergic component from inhalation of molds, dust and other air pollution as well as the triggering respiratory infection.

Part V – Leukemias, Lymphomas and other Malignancies
Ozone is an effective adjunct to high-pH therapy and other treatment methods of the Life Science Universal (LSU) modalities for these conditions. Ozone is a valuable adjunct for the treatment of Equine Sarcoids (generally in younger horses) and SquamousCell Carcinoma (most frequently in older horses). Ozone is particularly effective against any blood and malignant disease caused by viruses and bacteria such as Bovine Leukosis, Canine Malignant Lymphomas, Feline Lymphosarcoma, Feline Leukemia and lymphoproliferative disorders in turkeys, chickens and zoo animals.

Part VI – Rectal and Other Typical Applications of Ozone
Rectal ozone insufflations are a powerful adjunct to the treatment of both infectious and noninfectious diseases of the digestive tract. Ozone is effective in reducing intestinal parasites (helminths), viruses and rickettsiae (see part I, e.g. Rotavirus and Ehrlichia in horses), bacteria (see Part III, e.g. enterotoxigenic E. coli, Salmonella spp., Rhodococcus (Corynebacterium equi in horses), protozoa and fungi (see Part IV, e.g. Eimeria spp. and Aspergillus fumigatus in horses) and algae (Prototheca spp.). Ozone is effective in diarrhea and inflammatory bowel disease of horses. Vaginal ozone insufflations are effective against vaginal Candidiasis (see Part IV, Vaginitis, Equine Coital Exanthema (EHV-3), Contagious Equine Metritis (see Part III). Intramammary ozone application instead of antibiotics is effective for mastitis in large animals, e.g. mastitis in mares caused by Streptococcus zooepedemicus, S. equi, S. equisimilis, S. agalactiae and S. viridans.

Intra-articular ozone is effective for Septic Arthritis

Topical ozone is effective for dermatomycosis, osteomyelitis and infected wounds, fistulae (e.g. fistulous withers and poll evil, i.e. inflammation of supraspinous and supra-atlantal bursae caused equine and bovine udder diseases.

Ozonated Water (O3 x H2O)

Ozonated water has obvious multiple beneficial applications in veterinary medicine and surgery.


Important note from Ozone Services: Recommendations in terms of dosages, concentrations, volumes and flow rates outlined in Part VI are extremely high. We suggest starting with more conservative approach (and increase dosages if necessary later on).


Veterinarians only in the above cases.